Necessary Niacinamide


We all know that for about the past 50 years antibiotics have been greatly overused in people and animals. This abuse of oft needed antibiotics has created a period of difficulty wherein most antibiotics no longer are effective when necessary. If you're a regular reader of Natural Health News, the internet's first natural news site, you recognize that we have informed readers on the many helpful uses of niacin, niacinamide, or as it is commonly known, vitamin B3. Now a new study shows us what may be another valuable use -
Vitamin B3 offers superbug protectionThe September, 2012 issue of The Journal of Clinical Investigation reported the discovery of Cedars-Sinai researchers of a protective effect for vitamin B3 against methicillin-resistant Staphylococcus aureus (MRSA), a type of staph infection that is resistant to antibiotic treatment. The finding is the result of research concerning a rare disorder known as neutrophil-specific granule deficiency, which involves a mutation in the gene CEBPE that regulates some of the body's antimicrobial factors. Afflicted individuals have weakened immune systems that render them vulnerable to infections such as staph. "Our goal in studying a rare disorder is that it may give us broad insight into the immune mechanisms that protect healthy individuals against staph infections," noted first author Pierre Kyme, PhD, who is a researcher at Cedars-Sinai's Division of Pediatric Infectious Diseases in the Maxine Dunitz Children's Health Center and the Immunobiology Research Institute. "We found that if you over-express the gene in normal individuals, the body's immune cells do a better job of fighting off infection." The team determined that a high dose of a form of vitamin B3 known as nicotinamide or niacinamide stimulates CEBPE, which enhances white blood cells' ability to combat staph infections. When the vitamin was tested in human blood, it boosted the immune system's staph-killing ability up to 1,000-fold in a matter of hours compared to treatment with saline. And in mice that received injections of 250 milligrams nicotinamide per kilogram body weight prior to staph infection, bacterial counts in the animals' spleens and kidneys were 100-fold lower after 48 hours compared with animals injected with saline. The researchers suggest that targeting CEBPE with other compounds than nicotinamide could also help treat staph infections. Senior coauthor and Cedars-Sinai professor of medicine Phillip Koeffler, MD remarked that "There's more research to be done, but we believe that vitamin B3, and other compounds that are able to increase the activity of this particular gene, have the potential to be effective against other antibiotic-resistant bacteria in addition to strains of staph." "It's critical that we find novel antimicrobial approaches to treat infection and not rely so heavily on antibiotics," stated pediatric infectious disease physician and coauthor George Liu, MD, PhD, of Cedars-Sinai's Maxine Dunitz Children's Health Center. "That's why this discovery is so exciting. Our research indicates this common vitamin is potentially effective in fighting off and protecting against one of today's most concerning public health threats." SOURCE

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Cholesterol, Dementia, Schizophrenia, Detoxification,

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Calculating Cholesterol

Natural Health News has over eight (8) pages of articles addressing the cholesterol charade.  I am posting the top four (4) in light of the new push to get more people on a very dangerous drug that in reality has no real benefit to protect you from cardiovascular disease.
What statin drugs and other anticholesterol pharmaceuticals do is harm your health in so many other ways it is almost unfathomable that doctors them selves do not do more deep research on the concept.
You are at risk of muscle damage and kidney failure, heart failure, liver failure, diabetes, dementia, cancer and many more health derangements should you fall into this drug deception.
There are many safer and more natural ways to keep cholesterol in balance.  It is something you need not something to be depleted.
If you are interested in balancing cholesterol please contact us for more information and natural suggestions that do work with a lack of serious adverse effects.
And consider this -  Misled over the benefits of statins

Natural Health News: Cholesterol: Another Wrong Conclusion
Feb 21, 2011
I don't know where people's heads have been since the cholesterol bonanza began, but my stand is that these pundits overlooked a known fact, which now seems to be getting press after some 30 years. It's triglycerides!
Dec 23, 2008
UPDATE: Women in Government have a new ad campaign to push you to get cholesterol testing. This same organization has been behind the Gardasil propaganda campaign. For women especially, it is very important to get ...
Feb 23, 2008
Some studies have linked low cholesterol levels to higher death rates from cancer in general, Dr. Kouichi Asano, of Kyushu University, Fukuoka, and colleagues explain in the International Journal of Cancer. "With respect to ...
Nov 14, 2008
It's been going this way for a while: even healthy people should be on the cholesterol-reducing drugs known as statins. That, in a nutshell, is the verdict of a study published over the weekend which found that even in people ...


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Can we please hear both sides

Another pertussis cluster has led to the banning of non-vaccinated children from a school district in the Tucson area.  In all the news reports the issue of "non-vaccinated children" is the target or emphasized catch phrase.

I recall writing an article in the mid 90s after interviewing a California (MD) pediatrician who also included homeopathy in his practice.  His emphasis was that it is the non vaccinated child who is always the healthiest and has the most resistance to disease.

From NHN 2008: New Focus: Responding to Specific Queries

Now the idea today is that it is the non-vaccinated adult whose childhood vaccine has worn off and has not gotten a booster shot may be the new target.  Or it could be a combined attack.

A funny way to approach public health if you ask me, after spending the bulk of my work over decades with a strong public health focus.

Sadly little has changes at WA DOH since Selecky's departure.  Inslee replaced her with another non- responsive bureaucratic hack.

Maybe, prhaps, this article will get some courageous health care providers thinking outside the box and give this a shot.

But alas, "here we are."***

While it is a tragedy that people are dying from the current pertussis outbreak, I believe it is important for facts rather than propaganda be provided to the community at large.
The AMA (American Medical Association) knew in the late 1920s that pertussis vaccine caused neurological problems.
Now we know that the pertussis vaccine is often associated with whooping cough outbreaks and many who have had the vaccine contract the disease.
And of course the friendly people at WA DOH are announcing everywhere that the only thing that will help this is to get the jab.
New Article re: WA DOH Vaccines and Fluoride
I encourage people to get the facts before you get the shot because the government or anyone giving out these vaccines is required by law to explain it to you, and give you the risk and benefit data as well.  Usually you are not provided with this information in my experience.
You are probably not told that for whooping cough especially, that vitamin C is a valid and effective help.  Vitamin A in the oil form (not single beta carotene) in short runs of high doses will help fight off pneumonia, and it works well with vitamin C.  Usually I use liposomal vitamin C and Hanna Kroeger’s Sunny A.

Babies Sleep Better If They Are Drugged And Vaccinated In The Afternoon

Here is some information from a 1937 medical journal addressing this concern -
“Ascorbic acid has a definite effect in shortening the period of paroxysms from a matter of weeks to a matter of days. We have not checked by cough plates or otherwise in this preliminary work to see whether the infectivity subsides simultaneously with the spasmodic symptoms, but are continuing with a larger series of cases in which these and other tests will be employed.

TABLE

Case
Age
(years)
Sez
Contact
Duration of
Symptoms
Treatment
Results
1
R.T.
6
M
School
6 weeks—typical
150 mg. per day
7 days—cough reduced markedly
10 days—cough disappeared
2
C.H.
1�
M
Unknown
Temperature 102 F.
Bronchopneumonia
when men
3 weeks—typical
10 days “fever”
at home
inhalations
sinapisms
expectorants
}3 daysNo effect
7 days—temperature normal, cough reduced
14 days—cough disappeared
175 mg. daily—11 dys
3
M.C.
12
M
School
10 days—typical
200 mg. daily
6 days—cough reduced
13 days—only occasional night coughs
15 days—all cough absent
4
J.P.
6
F
School
over 4 weeks—
typical
200 mg. daily
3 days—cough less, no vomiting
7 days—occasional cough
5
B.O.
2�
M
Known case
2 weeks—typical
250 mg. daily
5 days—cough disappeared
6
H.F.
7
M
School
2 weeks—typical
375 mg. daily
4 days—cough less
9 days—night cough only
11 days—all cough absent
7
E.H.
22

Maid
Child in house had
whooping cough
4dys., paroxysmal
cough, vomited
once, no whooping
500 mg. daily—3 days
125 mg. daily.
4 days—cough less, no vomiting
6 days—coughed only once in 2 days
11 days—cough absent
8
B.P.
4
M
Known case
10 days—typical
500 mg. daily—4 days
250 mg. daily—4 days
5 days—cough disappeared
9
M.W.
6�
F
School
2 weeks—typical
500 mg. daily—4 days
250 mg. daily—5 days
4 days—cough reduced
7 days—coughed once in 24 hours
9 days—cough disappeared
10
W.C.
4�
F
Sister (Case 9)
1 week—typical
500 mg. daily—4 days
250 mg. daily—5 days
Same as for Case 9
The dosages used have been empirical with a tendency to use larger doses early in the disease as our experience of its effects progressed. The acid is available at reasonable prices, and the danger of overdosage seems negligible. Animals have received 2,000 times their estimated requirements without any deleterious effects. Any excess is excreted by the kidneys.

CONCLUSIONS

  1. A method has been described for the treatment of whooping cough by ascorbic acid (vitamin C).
  2. Ascorbic acid definitely shortens the paroxysmal stage of the disease, particularly if relatively large doses are used early in the disease.
The ascorbic acid used by us was the Hoffmann-LaRoche product sold under the trade name of “Redoxon”. Grootton and Beszonoff 4 have shown that the product is identical chemically, physically and biologically with the original product prepared by Szent-Gy�rgi.

REFERENCES

  1. , T.: Vaccination against whooping cough, J. Am. M. Ass., 1933, 101: 137.
  2. , F.: Internat. Med. Digest, 1936, 29: 121.
  3. , H. H.: Whooping cough. Clin. J., 1936, 65: 246.
  4. , O. and Beszonoff, N.: Action de la vitamine C sur la toxine diphth�rique, et sensibilit� du bacille de la coqueluche vis-a-vis de l’hydroquinol et de le vitamine C. Ann. de l’Inst Pasteur, 1936, 56: 413.
  5. , P. and Sala, T.: Rev. fran�. De P�d., 1921. 4: 509. (Quoted by Grootton and Beszonoff).
  6. , J. and Niederberger, W.: Vitamin C In der Pneumonie-Behandlung., M�nch. med. Wochschr.. 1936, 83: 2074.
  7. , A.: Beobachtungen �ber Ascorbins�urewirkung bei der krupp�sen Pneumonie, Wien. Arch. f. inn. Med., (in press). (Quoted by Gander and Niederberger).
  8. , G. J. and Daniels, A. L: Vitamin C studies with children of pre-school age, J. Nutrit., 1936. 12: 15.
  9. , O. A. and King, C. G.: The distribution of vitamin C in plant and animal tissues and its determination, J. Biol. Chem., 1933. 103: 687.
  10. , M. Almaden, P. and King, C.G.: Vitamin content of human tissues, J. Biol. Chem., 1934, 106: 525.

From The Canadian Medical Association Journal, Volume 37, August 1937, Number 2, pp. 134-136″
This article was originally entered here in April 2012: 
http://blog.seattlepi.com/naturalnotes/2012/04/04/can-we-please-hear-both-sides/

*** with thanks to Baba Ram Das and Bill Greenberg, MD (Harvard)
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FLU FOR YOU? or Prevention

The fact is the practice of flu vaccination in the elderly is not based on evidence, but an article of faith.
Should the Elderly Get the FLU jab? 

Use the search window in the right column to find our numerous posts on vaccines, flu, vitamin D, vitamin C, and more Natural Health News to keep you healthy and well...

From Dr Eisenstein
 

The risk of children suffering from flu can be reduced by 50% if they take vitamin D, doctors in
Japan have found. The finding has implications for flu epidemics since vitamin D, which is
naturally produced by the human body when exposed to direct sunlight , has no significant side effects, costs little and can be several times more effective than antiviral drugs or vaccines according to research in the American Journal of Clinical Nutrition.

Only one in ten children, aged six to 15 years, taking the sun shine vitamin in a clinical trial came down with flu compared with one in five given a dummy tablet. Mitsuyoshi Urashima, the Japanese doctor who led the trial, told The Times that vitamin D was more effective than
vaccines in preventing flu.

Vitamin D was found to be even more effective when the comparison left out children who were already given extra vitamin D by their parents, outside the trial. Taking the sunshine vitamin was then shown to reduce the risk of flu to a third of what it would otherwise be.

Dr. Damien Downing, a doctor and medical consultant has publicly stated that governments "do like" epidemics as a chance to impose their will. The London based doctor has been advising patients to increase their vitamin D intake rather than get the vaccine.

You might be shocked to know that there are many physicians in both Canada and the United
States who prescribe as much as 50,000 IU of vitamin D daily as a treatment for a long list of
chronic diseases.

Dr. John Cannell, MD, suggests high dose vitamin D (50,000 IU) be consumed for three days at the first sign of a cold or the flu. If you have an infection, the truth is you need more vitamin D. In other words, vitamin D acts as a natural antibiotic. It works against every type of microbe (viruses, bacteria, fungi and parasites).

Vitamin D deficiency is common during the winter months, especially in countries far north of
the equator. Vitamin D acts as an immune system modulator, preventing excessive production of inflammatory cytokines and increasing macrophage (a type of white cell) activity. Vitamin D
also stimulates the production of potent antimicrobial peptides in other white blood cells and in epithelial cells lining the respiratory tract, protecting the lungs from infection.

50 Percent Reduction In Flu Infections Using Vitamin D

Altogether 354 children took part in the trial. Vitamin D was found to protect against influenza A but not against the less common influenza B.

The trial, which was double blind, randomised , and fully controlled scientifically, was conducted by doctors and scientists from Jikei University School of Medicine in Tokyo, Japan.
The children were given a daily dose of 1200 IUs (international units) of vitamin D over a period of three months. In the first month children in the group taking the vitamin became ill just as often as those taking the dummy tablet. But by the second month, when the vitamin level in the children’s blood was higher, the advantage of the vitamin was clear.

The Japanese scientists, writing in the American Journal of Clinical Nutrition, say that the anti-
viral drugs zanamivir and oseltamivir reduce risk of flu infection by 8 percent in children who
have been exposed to infection, compared with a 50 percent or greater reduction with vitamin D.

Antivirals are typically more effective than vaccines for the influenza virus which suggests that
both forms of medical intervention would consistently fail in similar studies when pitted against
vitamin D.

Antivirals are expensive, and possibly toxic. Vitamin D additionally supports bone health but is believed to reduce risks of cancer, heart disease, diabetes and other illness, including various bacterial and viral infections.

The Japanese finding supports a theory that low blood levels of the sunshine vitamin occurring in winter explain why flu epidemics generally peak between December and March.

1. Get a Vitamin D blood test25(OH)D
2. Make sure your whole family has adequate blood levels of Vitamin D this flu season (>50 to 80ng/ml). Most children and adults Vitamin D blood level is <30ng font="" ml.="">
3. Adults .................................. 5,000 IU daily.
4. Children ............................... 1,000 IU/25lbs.
5. Chronic conditions....................... 10,000IU daily 
6. At the first symptoms of a cold or flu 1,000IU/ lb. daily for 7 days.
 
Examples:
 50 lb daily         50,000IU daily.   
 
100 lb daily       100,000IU daily.
150 lb daily       150,000IU daily.
200 lb daily       200,000 IU daily.

NB from Natural Health News: 

Vitamin A will assist in protecting lung health and against pneumonia. Vitamin E is also helpful to carry oxygen across the alveolar membrane in the lungs into the blood.

Healthy fat in your diet is required to absorb Vitamins A-D-E-K.

Add adequate daily vitamin C and probiotics. Always stay hydrated.
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